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Conditions of optimal B-Cell Activating Factor Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
BAFF binds to tnfrsf13b/taci and tnfrsf17/bcma. Tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. A third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response.
B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays.
Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin.
BP000059-CYT-545: Recombinant Human B cell Activating Factor (BAFF), His Tag Protein
Source: E. Coli-derived.
A single, non-glycosylated polypeptide chain containing 190 amino acids and having a molecular mass of 21 kDa. The BAFF His tag fusion protein is purified by proprietary chromatographic techniques.
Purity: > 95% by RP-HPLC and SDS-PAGE.
Formulation: Recombinant His Tag BAFF contains 20 mM Tris buffer pH-8 and 5 mM DTT.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
BAFF Antibodies:
BAFF Polyclonal Antibody
BAFF Monoclonal Antibody
BAFF ELISA Kits:
Mouse BAFF ELISA Kit
Human BAFF ELISA Kit
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