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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal APP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Amyloid beta A4 protein (APP) functions as a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form a number of peptides. A number of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to stimulate transcriptional activation, whereas others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. APP gene mutations are implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
BP002122-PRO-1080: Recombinant Human Amyloid beta (A4) Precursor Protein (APP)
Source: E. Coli-derived.
Recombinant Human Amyloid beta (A4) Precursor Protein (APP) is a single, non-glycosylated polypeptide chain containing 308 amino acids (18-289 a.a) and having a molecular mass of 34.7 kDa (Molecular size on SDS-PAGE will appear higher).
APP is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 85.0% as determined by SDS-PAGE.
Formulation: APP protein solution (1 mg/ml) containing 20 mM Tris-HCl buffer (pH 8.0) 20% glycerol, 0.1 M NaCl and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
APP ELISA Kits:
Human APP ELISA Kit
APP Antibodies:
APP Polyclonal Antibody
APP Monoclonal Antibody
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