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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Anthrax LF antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family(2).
PA005172-ANT-181: Anthrax LF Polyclonal Antibody
Rabbit Polyclonal Antibody.
Applications: This polyclonal antibody can be used for detection of Anthrax LF protein in western blot. Not tested in other applications. Western blot analysis of Anthrax LF in recombinant protein at 1:1000 dilution.
Immunogen: The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 47-65 of the Anthrax LF protein (~90 kD).
Form of Antibody: 100ugs in 200ul PBS containing 0.2% gelatin and 0.05% sodium azide.
Isotype: Rabbit Ig.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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