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Home > Proteins & Peptides > A-Z Proteins  > AKR1C1 Enzyme

AKR1C1 Enzyme

Aldo-keto reductase family 1 member C1, DDH1, DDH, HAKRC, 20-alpha-HSD, DD1/DD2, HBAB, C9, DD1, H-37, MBAB, MGC8954, 2-alpha-HSD

Catalog No. Product Name Size List Price (US$) Quantity
BP000860-ENZ-496 Recombinant Human AKR1C1 20 ug 160.00
BP000860-ENZ-496 Recombinant Human AKR1C1 1 mg 2250.00
Description

Introduction
AKR1C1 transfers progesterone to its inactive state or in other words catalyzes the reaction of 20-alpha-hydroxy progesterone (20-alpha-OHP). In the liver and intestine. AKR1C1 transfers bile and monitors the intrahepatic bile acid concentration though it has a low bile-binding ability. AKR1C1 participates in myelin formation. AKR1C1 is part of the aldo/keto reductase superfamily, which has over 40 known enzymes which catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors thus display overlapping but distinct substrate specificity.

BP000860-ENZ-496: Recombinant Human AKR1C1 (Aldo-keto reductase family 1 member C1)

Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 343 amino acids (1-323 a.a.) and having a molecular mass of 38.9 kDa.
Specific activity: approximately 0.15 - 0.2 units/mg.
Purity > 90%, by SDS-PAGE.
Formulation: The AKR1C1 solution contains 20 mM Tris-HCl pH-8, 1 mM DTT and 20% glycerol.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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