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Actin beta Antibody

Beta-Actin Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000105-MA1115 beta-Actin Monoclonal Antibody 100 ug 350.00
Description

Background

The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al. (1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.

PA000105-MA1115: β-Actin Monoclonal Antibody

Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins.
Applications: Western blot: 0.25 ug/ml-0.5 ug/ml, Immunohistochemistry(P): 0.5 ug/ml-1 ug/ml.
Reactivity: Human, Mouse, Rat.
Immunogen: slightly modified β-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys,conjugated to KLH.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: 1.2% sodium acetate or neutral PBS. If 1 ml of PBS is used, the antibody concentration will be 100 ug/ml.
Clone: AC-15.
Isotype: Mouse IgG1.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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