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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal ?-Actin antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al. (1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.
PA000105-MA1115: β-Actin Monoclonal Antibody
Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins.
Applications: Western blot: 0.25 ug/ml-0.5 ug/ml, Immunohistochemistry(P): 0.5 ug/ml-1 ug/ml.
Reactivity: Human, Mouse, Rat.
Immunogen: slightly modified β-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys,conjugated to KLH.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: 1.2% sodium acetate or neutral PBS. If 1 ml of PBS is used, the antibody concentration will be 100 ug/ml.
Clone: AC-15.
Isotype: Mouse IgG1.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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