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ABCG4 Antibody

ATP-Binding Cassette, Subfamily G, Member 4; WHITE2; putative ABC transporter

Catalog No. Product Name Size List Price (US$) Quantity
PA000154-PA2067 ABCG4 Polyclonal Antibody 100 ug 350.00
Description

Background

ABCG4 (ATP-Binding Cassette, Subfamily G, Member 4), is a protein that in humans is encoded by the ABCG4 gene. The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily and is expressed predominantly in liver tissue. By genomic sequence analysis, Engel et al. (2001) mapped the ABCG4 gene to chromosome 11q23.3. Engel et al. (2001) demonstrated 5-fold induction of ABCG4 following treatment of normal monocyte-derived macrophages with the LXR and RXR agonists 9-cis retinoic acid and 22R hydroxycholesterol. Removal of cholesterol from macrophages by cyclodextrin decreased ABCG4 message levels.

PA000154-PA2067: ABCG4 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Form of Antibody: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
Reconstitution: 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Reactivity: Human, Mouse, Rat.
Purification: Immunogen affinity purified.
Applications: WB 0.1-0.5 ug/ml.
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ABCG4, different from the related mouse and rat sequences by one amino acid.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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