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Conditions of optimal 5-HT-3A antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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HTR3A (5-HYDROXYTRYPTAMINE RECEPTOR 3A), also called SEROTONIN 5-HT-3 RECEPTOR, is a member of the ligand-gated ion channel receptor superfamily. HTR3A is a neurotransmitter in the central and peripheral nervous systems that plays a role in many physiologic processes such as sleep, appetite, thermoregulation, pain perception, hormone secretion, and sexual behavior. Using fluorescence in situ hybridization, the HTR3 gene is assigned to 11q23.1-q23.2. The single-channel conductance for homomers of HTR3A is 0.4 pS. Replacement of 3 arginine residues unique to the HA-stretch of the HTR3A subunit by their HTR3B subunit counterparts increases single-channel conductance 28-fold. Ultrastructural studies of the Torpedo nicotinic acetylcholine receptor indicated that the key residues might frame narrow openings that contribute to the permeation pathway. The genomic structure of the HTR3A gene contains 7 exons and spans approximately 14.5 kb.
PA003819-PA1610: 5-HT-3A Polyclonal Antibody
Rabbit Polyclonal Antibody.
Application: WB: 0.1-0.5 ug/ml IHC-P: 0.5-1 ug/ml.
Reactivity: Human.
Reconstitution: 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human HTR3A.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other 5-HT-3A Antibody:
5-HT-3A Polyclonal Antibody
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