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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal HPD Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
4-Hydroxyphenylpyruvate Dioxygenase Isoform-1 is an Fe-containing enzyme, which catalyzes the second reaction in the catabolism of tyrosine the conversion of 4-hydroxyphenylpyruvate to homogentisate. Present as a homodimer, HPD uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. Flaws in the gene encoding HPD result in tyrosinemia type 3 and hawkinsinuria, two inborn defects of metabolism which are related to a number of symptoms, like mental retardation and seizures and hair and urine abnormalities.
BP000745-ENZ-015: Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) Enzyme
Source: E. coli-derived.
Predicted molecular mass: 47 kDa.
Purity: > 90% by SDS-PAGE.
Formulation: The HPD protein solution (1 mg/1 ml) is formulated in 20 mM Tris-HCl buffer (pH 8.0) 1 mM DTT, 50 mM NaCl and 20% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other 4HPPD Enzymes:
Recombinant Human 4HPPD Enzyme
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