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Home > Antibodies > A-Z Primary Antibodies > IL-12 Antibody

IL-12 Antibody

Interleukin 12

Catalog No. Product Name Size List Price (US$) Quantity
PA005215-ANT-435 IL-12B Monoclonal Antibody 20 ug 160.00
PA005215-ANT-435 IL-12B Monoclonal Antibody 100 ug 450.00
Description
BACKGROUND
IL-12, Interleukin 12, heterodimerizes with the IL12 p35 subunit to form IL12 and with the IL23 p19 subunit to form IL23. IL12b p 40 exists as a monomer and as a homodimer. This gene encodes a subunit of Interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The IL-12b gene contains 8 exons, the first and last of which are noncoding. By PCR analysis of DNA from rodent/human cell hybrids containing intact chromosomes or translocation chromosomes, the IL-12b gene is mapped to 5q31-q33.This cytokine has been found to be important for sustaining a sufficient a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

PA005215-ANT-435: IL-12? Monoclonal Antibody

Form of Antibody: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Immunogen: Anti-human IL12B mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human IL12B amino acids 23-328 purified from E. coli.
Purification: IL12B antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Applications: IL12B antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.

Storage/Stability: Stable for 1 year at -20? and 3 months at 4?. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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