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Conditions of optimal WHSC2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
WHSC2 (NELF-A) is a protein factor required for DRB-sensitive transcription. WHSC2 is one of the 5 components of the multisubunit NELF complex which cooperates with DSIF to repress RNA polymerase II elongation. The Wolf-Hirschhorn syndrome is a multiple malformation syndrome characterized by mental and developmental defects resulting from a hemizygous deletion of the distal short arm of chromosome 4 (4p16.3).
BP002090-PRO-062: Recombinant Human Wolf-Hirschhorn syndrome candidate 2 (WHSC2) Protein
Source: E. coli-?derived.
Recombinant Human Wolf-Hirschhorn syndrome candidate 2 (WHSC2) Protein fused with a 20 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 559 amino acids (1-539 a.a.) and having a molecular mass of 60.6kDa. The WHSC2 is purified by proprietary chromatographic techniques.
Purity: > 85% as determined by SDS-PAGE.
Formulation: The WHSC2 solution (0.25 mg/ml) 20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 5 mM DTT, 1 mM EDTA and 20% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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