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Conditions of optimal UBE2L3 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Introduction
Human Ubquitin-conjugating enzyme 7 (UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-B maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7.
BP000980-ENZ-342: Recombinant Human Ubiquitin-Conjugating Enzyme E2L3
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 154 amino acids & having a molecular mass of 17.9 kDa.
Purity > 95%, by RP-HPLC and SDS-PAGE.
Formulation: The protein contains 50 mM HEPES (pH-7.5) 150 mM NaCl, 1 mM DTT, and 10% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other UBE2L3 Enzymes:
Recombinant Human Ubiquitin-Conjugating Enzyme E2L3, His Tag
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