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Conditions of optimal UBE2D4 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Ubiquitin-conjugating enzyme E2 D4, also known as Ubiquitin carrier protein D4, Ubiquitin-protein ligase D4, HBUCE1, UBE2D4, is a ligase that belongs to the ubiquitin-conjugating enzyme family. UBE2D4 has been proposed to participate in Ubl conjugation pathway. UBE2D4 take part in post-translational protein modification, protein K6-linked ubiquitination, protein K11-linked ubiquitination, protein K27-linked ubiquitination, protein K29-linked ubiquitination, protein K48-linked ubiquitination, and protein K63-linked ubiquitination. UBE2D4 regulate of protein metabolic process. UBE2D4 accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2D4 able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked poly-ubiquitination.
BP001058-ENZ-179: Recombinant Human Ubiquitin-conjugating enzyme E2 D4 (UBE2D4) Enzyme
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 167 amino acids (1-147) and having a molecular mass of 18.8 kDa. UBE2D4 is fused to a 20 amino acid His-tag at N-terminus.
Purity: > 95% by SDS-PAGE.
Formulation: The SRGN solution (1 ug/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 0.1 M NaCl and 10% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other UBE2D4 Enzymes:
Recombinant Human UBE2D4 Enzyme
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