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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal UBE2B Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
This E2 enzyme encodes for the human homolog of the yeast DNA repair gene RAD6, which is induced by DNA damaging agents. UBE2B can conjugate ubiquitin to histone H2A in an E3- independent manner in vitro, and is essential for the multi-ubiquitination and degradation of N-end rule substrates. Additionally, UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
BP000975-ENZ-340: Recombinant Human Ubiquitin Conjugating Enzyme E2B (UBE2B)
Source: E. coli-derived.
Predicted molecular mass: 19 kDa.
Purity: > 95% by RP-HPLC and SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered concentrated (1 ug/ml) solution in 1X PBS and 1 mM DTT, pH 7.5.
Reconstitution: It is recommended to reconstitute the lyophilized UBE2B in sterile water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other UBE2B Enzymes:
Recombinant Human UBE2B Enzyme
Recombinant Human UBE2B Enzyme
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