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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TXNRD1 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
TXNRD1 belongs to the selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. TXNRD1 decreases thioredoxins as well as other substrates, and participates in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity serves as a potential treatment for cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
BP000887-ENZ-518: Recombinant Human Thioredoxin Reductase 1
Source: E. coli-derived.
a single, non-glycosylated, polypeptide chain containing 508 amino acids (161-647 a.a.) and having a molecular mass of 55.7 kDa.
Specific activity is 0.48-0.6 units/ml, and was measured in a coupled assay with DTNB and NADPH. The amount of TNB generated by NADPH was measured in absorbance at 412 nm.
Purity > 90%, by SDS-PAGE.
Formulation: TXNRD1 Human solution containing 1x PBS pH-7.4 & 10% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other TXNRD1 Enzymes:
Recombinant Human Thioredoxin Reductase 1 161-649 a.a.
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