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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TXN1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Thioredoxins are small disulphide-containing redox proteins (within the conserved Cys-Gly-Pro-Cys active site) that have been found in all the kingdoms of living organisms. Thioredoxin contains a single disulfide active site and serves as a general protein disulphide oxidoreductase. Thioredoxins are involved in the first unique step in DNA synthesis. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of two cysteine thiol groups to a disulphide, accompanied by the transfer of two electrons and two protons. The net result is the covalent interconversion of a disulphide and a dithiol. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. It has been suggested that thioredoxin may catalyze the formation of correct disulfides during protein folding because of its ability to act as an efficient oxidoreductant. This could be especially useful in refolding proteins expressed in E. coli. To this end, thioredoxin has been shown to act as a protein disulfide isomerase.
BP002025-PRO-333: Recombinant Yeast Thioredoxin-1 (TXN1) Protein
Source: E. coli-derived.
Recombinant Yeast Thioredoxin-1 (TXN1) Protein is a single, non-glycosylated, polypeptide chain having a molecular mass of 12.6 kDa.
The Specific activity of Recombinant Yeast Thioredoxin-1 (TXN1) Protein is 3 IU/mg.
Purity: > 95.0% as determined by (a) RP-HPLC; (b) SDS-PAGE.
Formulation: Each mg of protein contains 20mM phosphate buffer pH 7.4.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other TXN1 Proteins:
Recombinant E.Coli Thioredoxin-1 Protein
Recombinant Human Thioredoxin-1 Protein, His Tag
Recombinant Human Thioredoxin-1 Protein
Recombinant His Tag Thioredoxin-1 Protein
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