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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TRXR Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
TRXR is a ubiquitous enzyme which participates in various cellular processes such as cell growth, p53 activity, and protection against oxidation stress. The mammalian Thioredoxin reductase cleaves thioredoxins as well as non-disulfide substrates such as selenite, lipoic acids, lipid hydroperoxides, and hydrogen peroxides.
Thioredoxin reductase (TrxR/NTR), an enzyme belonging to the flavoprotein family of pyridine nucleotide-disulfide oxidoreductases. Thioredoxin reductase (TrxR), a component of the thioredoxin system, including thioredoxin (Trx) and NADPH, catalyzes the transfer of electrons from NADPH to Trx, acts as a reductant of disulfide-containing proteins and participates in the defense system against oxidative stresses.
BP000885-ENZ-278: Recombinant Yeast Thioredoxin Reductase (NADPH)
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain having a molecular mass of 36 kDa.
The specific activity was found to be 5 IU/mg.
Purity > 98%, by RP-HPLC and SDS-PAGE.
Formulation: Each mg of protein contains 20 mM phosphate buffer pH 7.4 and 0.15 M sodium chloride.
Reconstitution: It is recommended to reconstitute the lyophilized NTR in sterile 18 M?-cm H2O.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other TRXR Enzymes:
Recombinant E.coli Thioredoxin Reductase
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