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Conditions of optimal TRKB Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Introduction
TRK family tyrosine kinase receptor containing TrkA, TrkB and TrkC. Three TRK family proteins have different ligand specificities.They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3,, TRKC binds NT-4/5. At the protein sequence level,human and rat TRKB are greater than 90% identical and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low level.for example: kidneys, ovary, pancreas outside the nervous system.
BP001086-C507: Recombinant Human Tropomyosin-Related Kinase B (TRKB) Enzyme
Source: HEK 293-derived.
Recombinant Human Tropomyosin-Related Kinase B (TRKB) Enzyme is a secreted protein with sequence (Cys32-His430) of Human NTRK2 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
TrkB Antibodies:
TrkB Polyclonal Antibody
TrkB (Phospho-Tyr706+Tyr707) Polyclonal Antibody
TrkB (Phospho-Tyr705) Polyclonal Antibody
TrkB (Ab-705) Polyclonal Antibody
TrkB (Ab-515) Polyclonal Antibody
TrkB ELISA Kits:
Mouse trkB ELISA Kit
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