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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TRIM21 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.
BP002208-PRO-328: Recombinant Human Tripartite Motif Containing 21 (TRIM21) Protein
Source: Sf9 insect cells-derived.
Recombinant Human Tripartite Motif Containing 21 (TRIM21) Protein is a glycosylated, polypeptide chain having a calculated molecular mass of 54,922 Dalton. Recombinant Human Tripartite Motif Containing 21 (TRIM21) Protein is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
Purity: > 90% as determined by SDS-PAGE.
Formulation: TRIM21 is supplied in 20 mM HEPES pH 7.5, 0.01 mM EDTA and 0.02% SDS.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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