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TRIM21 Protein

Tripartite Motif Containing 21, 52 kDa Ro protein, Sjoegren syndrome type A antigen, SS-A, Ro(SS-A), RING finger protein 81

Catalog No. Product Name Size List Price (US$) Quantity
BP002208-PRO-328 Recombinant Human TRIM21 Protein 20 ug 160.00
BP002208-PRO-328 Recombinant Human TRIM21 Protein 1 mg 3600.00
Description

Introduction
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.

BP002208-PRO-328: Recombinant Human Tripartite Motif Containing 21 (TRIM21) Protein

Source: Sf9 insect cells-derived.
Recombinant Human Tripartite Motif Containing 21 (TRIM21) Protein is a glycosylated, polypeptide chain having a calculated molecular mass of 54,922 Dalton. Recombinant Human Tripartite Motif Containing 21 (TRIM21) Protein is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
Purity: > 90% as determined by SDS-PAGE.
Formulation: TRIM21 is supplied in 20 mM HEPES pH 7.5, 0.01 mM EDTA and 0.02% SDS.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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