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Conditions of optimal TREM-1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Triggering Receptor Expressed on Myeloid cells(TREM) is a transmenmbrane protein having a single Ig-like domain. TREM associates with the adapter protein,DAP12, to deliver an activating signal.TREM-1 is expressed on blood neutrophils and monocytes,and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock.Human TREM-1 share 42% aa sequence homology.
BP001084-C506: Recombinant Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM1) Protein
Source: HEK 293-derived.
Recombinant Human Triggering receptor expressed on monocytes 1 (TREM1) Protein is a secreted protein with sequence (Ala21-Val201) of Human TREM1 fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other TREM-1 Proteins:
Recombinant Human TREM-1 Protein
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