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Conditions of optimal TnT Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Troponin-T is one of three subunits that form the troponin complex of the thin filaments of striated muscle, it regulates muscle contraction in response to alterations in intracellular calcium ion concentration. TnTc is expressed only in the heart and has proved to be a specific biomarker for heart disease.
Mutations in TNNT2 are associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Alternative splicing results in many tissue-specific isoforms.
BP001868-PRO-342: Human Cardiac Troponin T (TnT) Protein
Source: Human Cardiac Tissue-derived.
Human Cardiac Troponin T has a molecular weight of approximately 35 kDa. The Cardiac troponin-T is purified using a combination of ion-exchange and affinity chromatography steps.
Purity: > 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation: Human Cardiac Troponin T in 6 M Urea, 250 mM NaCl, 50 mM Tris-HCl, 15 mM b-mercaptoethanol, 1 mM EDTA, pH-7.2.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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