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Conditions of optimal TNIP1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
TNFAIP3-interacting protein 1 (TNIP1) interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with a RIP- or TRAF2-mediated transactivation signal. Furthermore, TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and its overexpression can inhibit viral replication. TNIP1 can regulate matrix nuclear localization, both nuclear import of Preintegration complex (PIC) and export of GAG polyprotein and viral genomic RNA during virion production.
BP002214-PRO-005: Recombinant Human TNFAIP3 Interacting Protein 1 (TNIP1) protein
Source: E. coli-derived.
Recombinant Human TNFAIP3 Interacting Protein 1 (TNIP1) protein fused with a 20 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 458 amino acids (94-530 a.a.) and having a molecular mass of 51.8 kDa. The TNIP1 is purified by proprietary chromatographic techniques.
Purity: > 75.0% as determined by SDS-PAGE.
Formulation: The TNIP1 solution (0.25 mg/ml) contains 20 mM Tris-HCl buffer (pH 7.5), 20% glycerol, 5 mM DTT and 200 mM NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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