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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TNFSF12 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
TNFSF12 is a cytokine that is part of the TNF ligand family. TNFSF12 is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. TNFSF12 induces apoptosis through multiple pathways of cell death in a cell type-specific manner. TNFSF12 promotes proliferation and migration of endothelial cells, and therefore acts as a regulator of angiogenesis. TNFSF12 is expressed in adult heart, pancreas, skeletal muscle, small intestine, spleen and peripheral blood lymphocytes. TWEAK h induces NF-?B and chemokine secretion. TNFSF12 promotes proliferation and migration of endothelial cells.
BP000128-CYT-699: Recombinant Human TNF Ligand Superfamily Member 12
Source: HEK293-derived.
A Mw of 18.7 kDa containing a total of 169 amino acid residues.
Purity > 90% by SDS-PAGE.
Formulation: Filtered and lyophilized from 0.5 ug/ml in 20 mM Tris buffer and 50 mM NaCl pH-7.5.
Reconstitution: Add pyrogen free water to a working concentration of 0.5 ug/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
ApplicationsWB.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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