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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TIFA Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
TRAF-interacting protein with FHA domain-containing protein A (TIFA) is an adapter protein that mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, triggering the downstream activation of NF-kappa-B and AP-1 pathways. The TIFA protein stimulates the oligomerization and polyubiquitination of TRAF6, leading to the activation of TAK1 and IKK through a proteasome-independent mechanism.
BP002217-PRO-1041: Recombinant Human TRAF-interacting protein with FHA domain-containing protein A (TIFA)
Source: E. coli-derived.
Recombinant Human TRAF-interacting protein with FHA domain-containing protein A (TIFA) is a single, non-glycosylated polypeptide chain containing 208 amino acids (1-184 a.a.) and having a molecular mass of 24 kDa. TIFA is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: TIFA protein solution (0.5 mg/ml) containing 20 mM Tris-HCl buffer (pH 8.0), 20% glycerol and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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