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Conditions of optimal TICAM2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
TICAM2 belongs to the Toll/interleukin-1 receptor (TIR) family, a group of proteins which include the Toll-like receptors (TLRs). TICAM2, a cytoplasmic protein, physically bonds TLR4 and TICAM-1 and functionally transfers LPS-TLR4 signaling to TICAM-1, that sequentially activates IRF-3. TICAM2 takes part in IL1-triggered NF-kappa-B activation, operating upstream of IRAK1, IRAK2, TRAF6, and IKBKB.
BP002218-PRO-1036: Recombinant Human Toll-like receptor adaptor molecule 2 (TICAM2) protein
Source: E. coli-derived.
Recombinant Human Toll-like receptor adaptor molecule 2 (TICAM2) protein is a single, non-glycosylated polypeptide chain containing 259 amino acids (1-235) and having a molecular mass of 29.4 kDa. Recombinant Human Toll-like receptor adaptor molecule 2 (TICAM2) protein is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 85.0% as determined by SDS-PAGE.
Formulation: The TICAM2 solution (1 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 100 mM NaCl, 1 mM DTT and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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