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Conditions of optimal TGFA Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Transforming growth factor alpha, also known as ETGF, belongs to the EGF family of cytokines. It is a mitogenic polypeptide and secreted protein which expressed by monocytes, keratinocytes, and various tumor cells. TGFA contains two chains, protransforming growth factor alpha and transforming growth factor alpha. It can bind to the EGF receptor that synergistically with TGF beta to stimulate anchorage-independent cell proliferation and produce a mitogenic response. TGFA interacts with the PDZ domains of MAGI3, SDCBP and SNTA1. The interaction with SDCBP, is required for the targeting to the cell surface.
BP001068-C178: Recombinant Human Transforming Growth Factor alpha (TGF-α) Protein
Source: E. coli-derived.
Recombinant Human Transforming Growth Factor alpha (TGF-α) Protein is expressed with sequence (VAL40-val89) of Human TGF-α.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 10 mM Acetic Acid.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
TGF alpha Antibodies:
TGF α Polyclonal Antibody
TGF alpha ELISA Kits:
Human TGFα ELISA Kit
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