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Conditions of optimal TBCC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Tubulin folding cofactor C (TBCC) is a member of the TBCC family. TBCC has a role in the control of centrosome and Golgi apparatus positioning, with effects on cell shape and cell migration. Cofactor C is 1 of 4 proteins (cofactors A,D,E and C) engaged in the pathway leading to properly folded b-tubulin from folding intermediates. Cofactor E attaches to the cofactor D/beta-tubulin complex; their interaction with cofactor C subsequently causes the release of beta-tubulin polypeptides which are bound to the native state.
BP002230-PRO-1180: Recombinant Human Tubulin Folding Cofactor C (TBCC) Protein
Source: E. coli-derived.
Recombinant Human Tubulin Folding Cofactor C (TBCC) Protein is a single polypeptide chain containing 369 amino acids (1-346) and having a molecular mass of 41.7 kDa. Recombinant Human Tubulin Folding Cofactor C (TBCC) Protein is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 85.0% as determined by SDS-PAGE.
Formulation: The TBCC solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 100 mM NaCl, 1 mM DTT and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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