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Home > Antibodies > A-Z Primary Antibodies > Spectrin (alpha and beta) Antibody

Spectrin (alpha and beta) Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000087-MA1090 Spectrin (A and B) Monoclonal Antibody 100 ug 350.00
Description

Background

Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2.Spectrin mutations cause spinocerebellar ataxia type 5.

PA000087-MA1090: Spectrin (α and β) Monoclonal Antibody

Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human. No cross reactivity with other proteins.
Applications: Western blot: At 2-4 ug/ml with the appropriate system to detect spectrin in cells and tissues.
Reactivity: Human.
Immunogen: Human erythrocyte spectrin.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: Spe 1/2.
Isotype: Mouse IgG1.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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