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Conditions of optimal SOX2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Introduction:
Recombinant Human Sex determining region Y box 2 (Sox2) belongs to a diverse family of structurally-related transcription factors whose primary structure contains a high mobility group box domain. SOX2 is one of the important transcription factors required in induced pluripotent stem cells. SOX2 regulates the expression of multiple genes involved in embryonic development, including FGF-4, YES-1, ZFP206. SOX2 may as a switch in neuronal development, keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. It has been shown SOX2 can interact with PAX6.
BP001110-PRO-820: Recombinant Human Sex determining region Y box 2 (SOX2) protein
Source: E.coli-derived.
Recombinant Human Sex determining region Y box 2 (SOX2) protein is a single, non-glycosylated, polypeptide chain containing 208 amino acids (1-200 a.a.) and having a molecular mass of 23.1 kDa. Recombinant Human Sex determining region Y box 2 (SOX2) protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The SOX2 solution contains 20 mM Tris-HCl pH 8, 2 mM DTT, 0.2 M NaCl & 40% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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