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Conditions of optimal SOD1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Superoxide Dismutase [Cu-Zn] (SOD1) is a soluble cytoplasmic and mitochondrial intermembrane space protein that belongs to the Cu-Zn superoxide dismutase family. SOD1 binds copper and zinc ions and is one of three isozymes responsible for destroying free superoxide radicals in the body. SOD1 neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. The enzyme protects the cell against dangerous levels of superoxide. Zinc binding promotes dimerization and stabilizes the native form. Mutations in SOD1 cause a form of familial amyotrophic lateral sclerosis. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1) which is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis.
BP001655-PRO-648: Recombinant Human Superoxide Dismutase 1 (SOD1) Protein
Source: E. coli-derived.
Recombinant Human Superoxide Dismutase 1 (SOD1) Protein is a single monomeric non-glycosylated polypeptide chain containing 154 amino acids and having a total molecular mass of 15.9 kDa. Recombinant Human Superoxide Dismutase 1 (SOD1) Protein is purified by proprietary chromatographic techniques.
The specific activity of Recombinant Human Dismutase 1 (SOD1) protein is calculated by its ability to be more than 90 units/mg.
Purity: > 95.0% by RP-HPLC and SDS-PAGE.
Formulation: 0.2 um filtered solution contains 20 mM Tris-HCl pH 7.5 and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other SOD1 Proteins:
Recombinant Human SOD1 Protein
SOD1 Antibodies:
SOD1 Polyclonal Antibody
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