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SNPH Protein

Syntaphilin, KIAA0374, MGC46096, bA314N13.5

Catalog No. Product Name Size List Price (US$) Quantity
BP002257-PRO-545 Recombinant Human SNPH Protein 50 ug 160.00
BP002257-PRO-545 Recombinant Human SNPH Protein 1 mg 1800.00
Description

Introduction
Syntaxin-1, synaptobrevin, and SNAP25 cooperate to form the SNARE complex, which is needed for synaptic vesicle docking and fusion SNPH is a neuron-specific protein originally characterized as a binding partner of syntaxin-1. SNPH participates with SNAP25 for the binding to Syntaxin-1 and prevents the construction of the SNARE core complex, thus manageling free syntaxin-1 availability for the assembly of the SNARE complex and potentially regulating synaptic vesicle exocytosis. Expression Syntaphilin appears to be brain-specific. SNPH is an inhibitor of both SNARE-based fusion and dynamin-mediated endocytosis.

BP002257-PRO-545: Recombinant Human Syntaphilin (SNPH) Protein

Source: E. coli-derived.
Recombinant Human Syntaphilin (SNPH) Protein is a single, non-glycosylated polypeptide chain containing 444 amino acids (1-424) and having a molecular mass of 48.2 kDa. Recombinant Human Syntaphilin (SNPH) Protein is fused to 20 amino acid His-Tag at N-terminus and purified by standard chromatography techniques.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The Syntaphilin protein solution contains 20 mM Tris-HCl pH 8, 1 mM DTT and 10% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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