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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal SNF8 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
SNF8 belongs to the SNF8 family of vacuolar sorting proteins and is restricts to both the nucleus and the cytoplasm. SNF8 is a subunit of the endosomal sorting complex essential for transport II (ESCRT-II), which is necessary for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway facilitates transfer of transmembrane proteins into the lumen of the lysosome for degradation. Additionally, the ESCRT-II complex takes part in transcription regulation by contributing to derepression of transcription by RNA polymerase II, probably by its interface with ELL.
BP002259-PRO-1135: Recombinant Human SNF8 ESCRT-II complex subunit homolog (S. cerevisiae) (SNF8) Protein
Source: E. coli-?derived.
Recombinant Human SNF8 ESCRT-II complex subunit homolog (S. cerevisiae) (SNF8) Protein
is a single polypeptide chain containing 282 amino acids (1-258) and having a molecular mass of 31.4 kDa. Recombinant Human SNF8 ESCRT-II complex subunit homolog (S. cerevisiae) (SNF8) Protein is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The SNF8 solution (0.25 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 2 mM DTT and 50% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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