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SIRT3 Protein

Sirtuin 3, SIR2-like protein 3, Sir2-like 3, NAD-dependent deacetylase sirtuin-3, mitochondrial

Catalog No. Product Name Size List Price (US$) Quantity
BP002075-PRO-462 Recombinant Human Sirtuin 3 protein 10 ug 160.00
BP002075-PRO-462 Recombinant Human Sirtuin 3 protein 1 mg 5200.00
Description

Introduction
SIRT3 is a member of a family of proteins called Sirtuin. Proteins of the Sirtuin family are characterized by a Sirtuin core domain and grouped into four classes. The roles of human Sirtuins are numerous and are important in aging prosseses, stress resistance and metabolic regulation. SIRT3 shows NAD+-dependent deacetylase activity in the mitochondria. Over-expression of SIRT3 causes increased levels of the mitochondrial uncoupling protein 1. Also, in certain breast cancers the levels of SIRT3 protein are found to be extremely high.

BP002075-PRO-462: Recombinant Human Sirtuin 3 (SIRT3) protein

Source: E. Coli-derived.
Recombinant Human Sirtuin 3 (SIRT3) protein is a single, non-glycosylated polypeptide chain containing 303 amino acids (118-399a.a.) and having a molecular mass of 33.5 kDa. Recombinant Human Sirtuin 3 (SIRT3) protein is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 95.0% as determined by SDS-PAGE.
Formulation: The SIRT3 protein solution (1 mg/ml) is formulated in 20 mM Tris-HCl buffer (pH 8.0) 1 mM DTT, 0.1 M NaCl, 10% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

SIRT3 Antibody:
SIRT3 Polyclonal Antibody

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