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Conditions of optimal SF3B14 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
SF3B14 is a 125 amino acid nuclear protein which is a component of the splicing factor 3b complex. Splicing factor 3b is involved with s with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. SF3B14 which is required for the splicing of pre-mRNA enters the spliceosome and connect with the pre-mRNA branch site facilitating the interaction of snRNP with the branch sites of U2 and U12 of the 17S U2 and the 18S U11/U12 snRNP complex.
BP002276-PRO-105: Recombinant Human Splicing Factor 3B, 14 kDa Subunit (SF3B14) Protein
Source: E. coli-derived.
Recombinant Human Splicing Factor 3B, 14 kDa Subunit (SF3B14) Protein fused with a 20 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 145 amino acids (1-125a.a.) and having a molecular mass of 16.7 kDa. The SF3B14 is purified by proprietary chromatographic techniques.
Purity: > 95.0% as determined by SDS-PAGE.
Formulation: The SF3B14 solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 5 mM DTT, 1 mM EDTA and 30% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
SF3B14 Antibody:
SF3B14 Polyclonal Antibody
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