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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Seprase performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Seprase is a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. Seprase is a homodimeric integral membrane gelatinase, which is part of the serine protease family. Seprase is expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Seprase protein has a role in the control of fibroblast growth or epithelial-mesenchymal interactions throughout development, tissue repair, and epithelial carcinogenesis.
BP000726-ENZ-465: Recombinant Human Fibroblast Activation Protein Alpha (Seprase) Protein
Source: E. coli-derived.
A single, non-glycosylated, Polypeptide chain containing 203 amino acids (559-761 a.a.) and having a total Mw of 48 kDa.
Formulation: Seprase is supplied in 50 mM Tris-Acetate, pH-7.5, 1 mM EDTA and 20% Glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
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