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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal scIC2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Introduction
Troponin Complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, Troponin I, Troponin T and TroponinC. Each subunit is responsible for part of Troponin Complex function. E.g. Troponin I inhibits ATP-ase activity of acto-myosin.Troponin T and Troponin Iare presented in cardiac muscles in different forms than in skeletal muscles. Purified subunits of rcTnI, rcTnC and rcTnT are recomplexed in vitro under appropriate conditions.
BP001864-PRO-346: Recombinant Single Chain Cardiac Troponin I-C 2nd generation (scIC2) Protein
Source: E. coli-derived.
Recombinant Single Chain Cardiac Troponin I-C 2nd generation is a single, non-glycosylated, polypeptide chain (aa28-110-Linker-cTnC), having a molecular weight of 30 kDa. 1 mg of scIC2 is equivalent to 0.82 mg of full length human cardiac TNI on a molar basis. The scIC2 is purified by proprietary chromatographic techniques.
Applications: Immunoassays and western blot.
Purity: > 91.0% as determined by SDS-PAGE.
Formulation: The protein solution contains 20 mM Tris-HCl, 250 mM NaCl and 50% glycerol, pH 7.5.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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