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Conditions of optimal RGS1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
RGS1 belongs to the regulator of G-protein signaling family. The RGS1 protein is situated on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif termed the RGS domain. RGS1 diminish s the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and performing as a GTPase activating protein (GAP), boosting the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, creating inactive G-protein heterotrimers, thus terminating the signal.
BP002411-PRO-1118: Recombinant Human Regulator of G-Protein Signaling 1 (RGS1)
Source: E. coli-derived.
Recombinant Human RGS1 protein is a single, non-glycosylated polypeptide chain containing 233 amino acids (1-209 a.a) and having a molecular mass of 26 kDa. RGS1 protein is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 90% as determined by SDS-PAGE.
Formulation: RGS1 protein solution (0.25 mg/ml) containing 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
RGS1 Antibody:
RGS1 Polyclonal Antibody
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