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Conditions of optimal RDBP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
RDBP is a putative RNA binding protein. RDBP protein is one of the five components of the multisubunit NELF complex which collaborates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation needs a complex interaction between positive transcription elongation factor b and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. RDBP has a functional RNA-binding domain, whose mutations impair transcription repression without affecting known protein-protein interactions.
BP002299-PRO-181: Recombinant human RD RNA Binding Protein (RDBP) Protein
Source: E. coli-derived.
Recombinant human RD RNA Binding Protein (RDBP) Protein is a single, non-glycosylated polypeptide chain containing 400 amino acids (1-380a.a.) and having a molecular mass of 45.4 kDa. Recombinant human RD RNA Binding Protein (RDBP) Protein is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 85% as determined by SDS-PAGE.
Formulation: The RDBP protein solution (1 mg/ml) is formulated in 20 mM Tris-HCl buffer (pH 8.0), 100 mM NaCl, 2 mM DTT and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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