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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal RCN1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
RCN1 is a calcium-binding protein which binds calcium and controls calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment. RCN1 withholds six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand.
High conservation of amino acid residues outside of these motifs, in relation to mouse reticulocalbin, is consistent with a biochemical function further to that of calcium binding. In human endothelial and prostate cancer cell lines RCN1 protein is localized to the plasma membrane.
BP002420-PRO-544: Recombinant Human Reticulocalbin 1 (RCN1) Protein
Source: E. coli-derived.
Recombinant Human RCN1 protein is a single, non-glycosylated polypeptide chain containing 341 amino acids (30-331 a.a.) and having a molecular mass of 40.4 kDa (real molecular weight on SDS-PAGE will be shift up). The RCN1 protein is fused to 39 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Purity: > 80.0% as determined by SDS-PAGE.
Formulation: 1 mg/ml solution containing 20 mM Tris-HCl pH-8, 1 mM DTT, 0.1 M NaCl & 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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