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RAB5B Protein

RAB5B, Member RAS Oncogene Family, Ras-related protein Rab-5B

Catalog No. Product Name Size List Price (US$) Quantity
BP002351-PRO-056 Recombinant Human RAB5B, Member RAS Oncogene Family Protein 20 ug 160.00
BP002351-PRO-056 Recombinant Human RAB5B, Member RAS Oncogene Family Protein 1 mg 2700.00
Description

Introduction
Ras-related protein Rab-5B (RAB5B) belongs to the Rab family of small (monomeric) G proteins. RAB5B is involved in endocytosis and recycling of cell surface molecules. RAB5B interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of RAB5B abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection.

BP002351-PRO-056: Recombinant Human RAB5B, Member RAS Oncogene Family (RAB5B) Protein

Source: E, coli-derived.
Recombinant Human RAB5B protein fused with a 23 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 238 amino acids (1-215 a.a.) and having a molecular mass of 26.1 kDa. The RAB5B protein is purified by proprietary chromatographic techniques.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: The RAB5B solution (1 mg/ml), 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 20% glycerol and 0.2 M NaCl.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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