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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal RAB5B Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Ras-related protein Rab-5B (RAB5B) belongs to the Rab family of small (monomeric) G proteins. RAB5B is involved in endocytosis and recycling of cell surface molecules. RAB5B interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of RAB5B abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection.
BP002351-PRO-056: Recombinant Human RAB5B, Member RAS Oncogene Family (RAB5B) Protein
Source: E, coli-derived.
Recombinant Human RAB5B protein fused with a 23 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 238 amino acids (1-215 a.a.) and having a molecular mass of 26.1 kDa. The RAB5B protein is purified by proprietary chromatographic techniques.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: The RAB5B solution (1 mg/ml), 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 20% glycerol and 0.2 M NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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