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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal RAB23 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
RAB23 belongs to the Rab family of proteins and is restricted to the cytoplasmic side of the cell membrane. RAB23 takes part in intracellular protein transportation and signal transduction facilitated by small GTPases. RAB23 is a vital negative regulator of the Sonic hedgehog signaling pathway. Alterations in the gene encoding RAB23 are the origin for Carpenter syndrome a disorder which can cause obesity, cardiac defects, polysyndactyly and craniosynostosis.
BP002336-PRO-977: Recombinant Human RAB23, Member RAS Oncogene Family (RAB23) Protein
Source: E. coli-derived.
Recombinant Human RAB23 protein is a single, non-glycosylated polypeptide chain containing 254 amino acids (1-234) and having a molecular mass of 28.5 kDa. RAB23 protein is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The RAB23 solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 0.1 mM PMSF and 30% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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