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Conditions of optimal PTPS Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Introduction
6-PyruvoylTetrahydropterin Synthase is part of the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. 6-PyruvoylTetrahydropterin Synthase catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, is a necessary cofactor and regulator of a range of enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in 6-PyruvoylTetrahydropterin Synthase gene result in hyperphenylalaninemia.
BP000904-ENZ-471: Recombinant Human 6-Pyruvoyl Tetrahydropterin Synthase (PTPS)
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 165 amino acids (1-145) and having a molecular mass of 18.5 kDa.
Purity > 95%, by SDS-PAGE.
Formulation: 6-Pyruvoyl Tetrahydropterin Synthase is formulated in 20 mM Tris-HCl buffer pH-8, 1 mM DTT and 20% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
PTPS Antibodies:
PTPS Monoclonal Antibody
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