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PSMA6 Enzyme

Proteasome Subunit Alpha Type 6, PROS27, p27K, IOTA, Macropain iota chain, Multicatalytic endopeptidase complex iota chain

Catalog No. Product Name Size List Price (US$) Quantity
BP002730-ENZ-198 Recombinant Human Proteasome Subunit Alpha Type 6 Enzyme 10 ug 160.00
BP002730-ENZ-198 Recombinant Human Proteasome Subunit Alpha Type 6 Enzyme 1 mg 5200.00
Description

Introduction
PSMA6 belongs to the peptidase T1A family, which is a 20S core alpha subunit. The proteasome is a multicatalytic proteinase complex with an extremely organized ring-shaped 20S core structure. The core structure consists of 4 rings of 28 non-identical subunits; 2 rings consist of 7 alpha subunits and 2 rings consist of 7 beta subunits. PSMA6 is spread all over eukaryotic cells in large quantities and cleave peptides in an ATP/ubiquitin-dependent procedure in a non-lysosomal pathway.

BP002730-ENZ-198: Recombinant Human Proteasome Subunit Alpha Type 6 (PSMA6) Enzyme

Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 270 amino acids (1-246 a.a.) and having a molecular mass of 29.9 kDa. PSMA6 is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: PSMA6 protein solution (0.25 mg/ml) containing 20 mM Tris-HCl buffer (pH8.0), 100 mM NaCl, 1 mM DTT and 40% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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