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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal PRTN3 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Proteinase-3 is a neutral serine proteinase that belongs to the peptidase S1 family and Elastase subfamily. It contains one peptidase S1 domain and it is expressed mainly in neutrophil granulocytes. The primary function of Proteinase-3 is thought to be degradation of extracellular proteins at sites of inflammation, but excessive or prolonged proteolytic activity may cause harmful effects in the body. It is the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
BP000724-ENZ-075: Human Proteinase-3 (PRTN3) Enzyme
Source: Native-derived.
A natural antigen having a molecular mass of 25 kDa to 32 kDa due to glycosylation isoforms.
Purity: > 80% in the sum of different glycosylation isoforms according to following section as determined by SDS-PAGE and capillary electrophoresis.
Formulation: PRTN3 is supplied in 16 mM HEPES buffer pH-8.0, 400 mM NaCl, and 20% glycerol.
Applications: WB.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other PRTN3 Enzymes:
Recombinant Human PRTN3 Enzyme
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