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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal proNT3 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
proNT-3 (the precursor form of neurotrophin-3) functions through p75NTR and sortilin and induces neuronal apoptosis. In contrast, mature NT-3 interacts with Trk receptors and selectively promotes the survival, growth and differentiation of neurons. Since axon retrograde transport is crucial for neurotrophin signaling, proNT-3 also has an important role in the mechanism of retrograde signaling.
BP001010-CYT-015: Recombinant Human Pro-Neurotrophin-3 (proNT3) Protein
Source: E. coli-derived.
N-terminal sequence analysis: Asn-Asn-Met-Asp-Gln.
A single, non-glycosylated, polypeptide chain containing 239 amino acids and having a molecular mass of 27.4 kDa.
Purity: > 95% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in 20 mM PB, pH 8.0 and 300 mM NaCl.
Reconstitution: It is recommended to reconstitute the lyophilized proNT3 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other proNT3 Protein:
Recombinant Human proNT3 Protein
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