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Home > Antibodies > A-Z Primary Antibodies > Progesterone Receptor Antibody

Progesterone Receptor Antibody

NR3C3; nuclear receptor 3C3; PGR; PRGR; PR

Catalog No. Product Name Size List Price (US$) Quantity
PA000410-PA1413 Progesterone receptor/PR Polyclonal Antibody 100 ug 350.00
Description

Background

The progesterone receptor (PR) is an intracellular steroid receptor that specially binds progesterone in humans. PR has been a member of the steroid receptor superfamily. It is encoded by a single PGR gene residing on chromosome 11q22. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. It can be observed in human breast tissues. The proteins function as dimeric molecules in nuclei to regulate the transcription of target genes in a ligand-responsive manner.

PA000410-PA1413: Progesterone receptor/PR Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, Mouse, Rat. No cross reactivity with other proteins.
Applications: WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml.
Reactivity: Human, Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human PR, identical to the rat and mouse sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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