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Conditions of optimal PPP1R1A Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
BP000783-ENZ-366: Recombinant Human Protein Phosphatase Inhibitor-1 (PPP1R1A) Enzyme
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 179 amino acids and having a molecular mass of 20 kDa.
Purity: > 90% by RP-HPLC and SDS-PAGE.
Formulation: The PPP1R1A solution contains 50 mM Tris pH-8, 0.1 mM PMSF, 1 mM EDTA, 1 mM DTT & 10% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other PPP1R1A Enzymes:
Recombinant Human PPP1R1A Enzyme
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