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Conditions of optimal PPP1CC Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Introduction
Serine/Threonine-Protein Phosphatase PP1-Gamma Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1CC may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.
BP001692-ENZ-613: Recombinant Human Serine/Threonine-Protein Phosphatase PP1-Gamma Catalytic Subunit (PPP1CC) Enzyme
Source: E. coli-derived.
A single polypeptide chain containing 343 amino acids (1-323) and having a molecular mass of 39.1 kDa. PPP1CC is fused to a 20 amino acid His-tag at N-terminus.
Purity: >85% by reducing SDS-PAGE.
Formulation: The PPP1CC solution (0.25 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 200 mM NaCl, 2 mM DTT and 50% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other PPP1CC Enzymes:
Recombinant Human PPP1CC Enzyme
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