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Background Information:
A potent and selective mTOR inhibitor with IC50 = 8 nM. Highly selective against PI3K isoforms α, β, ?and δ (IC50 at 2000, 2200, 100 and 1300 nM, respectively), and DNA-PK (IC50 410 nM).
Reference:
1. Aspel, B., et al., Nat. Chem. Biol. 4, 691, 2008.
APIM050231: PP242
CAS No.: 1092351-67-1.
Molecular Formula: C16H16N6O.
Molecular Weight: 308.3.
Purity: > 99% (HPLC).
QC: LC/MS, 1HNMR, HPLC.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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