Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Conditions of optimal PER1 Antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
PER1 (Period, Drosophila, Homolog of), also known as PER or RIGUI, is a protein that in humans is encoded by the PER1 gene. By fluorescence in situ hybridization, Sun et al. (1997) mapped the human PER1 gene to 17p12. Sun et al. (1997) found that in mouse retina, the expression of rigui oscillated over a 24-hour period, with highest expression at onset of dark in a 12-hour light/dark cycle, i.e., expression rose during the light period and fell during the dark period. RNA abundance of rigui changed 2.9-fold between highest and lowest levels in mouse retina. Shigeyoshi et al. (1997) examined the effects of light on rigui, designated mouse Per1 by them, which exhibits robust rhythmic expression in the SCN. They found that Per1 is rapidly induced by short duration exposure to light at levels sufficient to reset the clock. Von Gall et al. (2002) demonstrated that cycling expression of the clock gene Per1 in rodent pituitary cells depends on the heterologous sensitization of the adenosine A2B receptor, which occurs through the nocturnal activation of melatonin mt1 receptors.
PA006389-PA2044: PER1 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug /ml.
Reactivity: Human, Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human PER1, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized. Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.