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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal PEDF Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Introduction
Serpin F1 is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. Serpin F1 is a new promising approach for the treatment of osteosarcoma and has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Levels of the natural ocular anti-angiogenic factor SentrinF1 (PEDF) is associated with proliferative retinopathy.
BP001013-CYT-553: Recombinant Human Pigment Epithelium-derived.Factor (PEDF) Protein, HEK
Source: HEK 293-derived.
A single, glycosylated, polypeptide chain containing 410 amino acids and having a molecular mass of 45.6 kDa.
Purity: > 95% by SDS-PAGE.
Formulation: The filtered (0.4 um) concentrated (0.5 ug/ml) protein solution was lyophilized with 20 mM Tris & 20 mM NaCl pH-7.5.
Reconstitution: It is recomnded to add deionized water to a working concentration of 0.5 ug/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other PEDF Proteins:
Recombinant Human PEDF Protein, His Tag
Recombinant Human PEDF Protein
Recombinant Human PEDF Protein
PEDF Antibodies:
PEDF Polyclonal Antibody
PEDF Monoclonal Antibody
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